Frequently asked questions about oocyte donation

Why be an oocyte donor?

Oocyte donation helps to achieve a desired pregnancy to woman who could not have children otherwise. There are different causes why these difficulties occur such as premature menopause or women who have undergone agressive treatments with radio- or chemotherapy.

What do I have to do to become a donor?

  1. Getting in touch with FIVclínic by phone, email or personally.

  2. Coming to an informative appointment in which the process and treatment are explained in detail, as well as answering any doubts the person might have.

  3. Once the decision of becoming a donor has made, she will be seen by a doctor in order to know her medical history. She will undergo a complete gynaecological exploration that includes a vaginal cytology and an ultrasound. If everything is fine, a general blood tests will be needed so as to determine the karyotype, the blood group and Rh and viral serology such as HIV, hepatitis B and hepatitis C.

  4. A phycologyst visit will be also made to confirm that there is no counter-indications in that regard. FIVclínic adapts to the donor’s timetables and needs by making the appointments all together and offering different alternative schedules.

If all the results of the process are correct, the doctor will set a month in which the donation will be carried out, according to the donor’s interests and priorities. Before the treatment begins, the informed consent will have to be signed.

What does the treatment consist of?

It is a hormonal treatment to stimulate the ovaries in order to obtain several ovules at the same time. This is necessary because in an assisted fertilisation not all the ovules are optimal to be fertilised and not all the fertilised ones develop to the embryo stage either.

We cannot ensure that all the embryos are suitable for being transferred into the uterus. It is a subcutaneous treatment that has to be initiated the second or third day after the menstruation period starts and it lasts around twelve and fifteen days. During the treatment, a periodical monitoring with an ultrasound and a blood test has to be done (every two days). Occasionally, it is necessary, just before the treatment, an intramuscular injection to inhibit the spontaneous function of the ovary.

Once the follicles have grown and are in an optimum mature stage, the follicular puncture is programed. It will be carried out in the operating room and it lasts between 20 and 25. It is an outpatient intervention and anesthesia with sedation will be given. After the puncture, a half an hour rest is required in an individualised and comfortable recovery room.

During the following two weeks, a medical monitoring will be needed. The last appointment is normally made after the menstruation , that is, a fortnight after the follicular puncture.

Has risks oocyte donation?

The hormonal treatment does not have any effect on the donor’s fertility. Every woman is born with a certain number of follicles in the ovaries and it does not increase during her life. In each menstruation cycle, some of theses follicles start the maturation process, however, when just one of them will achieve a complete maturation, that is, there is only one ovule. The rest of the follicles do not conclude the whole process.

Thanks to the hormonal treatment that the donor carries out, all of these missed follicles that do not complete the maturation process achieves to the final ovulation phase too. Only in exceptional cases -less than a 1% of the women- the treatment may provoke an excessive ovarian response, knwon as an ovarian hiperstimulation syndrome. It consists of a fluid retention, that is, a decreasing urine elimination, together with a physical discomfort that, occasionally, may require hospitalisation and a specific treatment to accelerate the recovery process, which it does not normally take too long.


Since the techniques used are simple, bloodless and a tracheal intubation is not required, it is highly unsual the existence of other types of complication related to the surgery or anesthesia. Even though all these risks are very unsuall, they are collected in the informed consent that the donor signs at the beginning of the treatment. Donors are allowed to repeat the ovule donation process several times as long as their health is not endangered. Nonetheless, it is reccommended not to exceed six stimulation cycles. If a donor wants to repeat it, she needs to wait a few months so as to start another one.

Which legal aspects have to be known?

Donation is considered by law a voluntary, anonimous and altruistic action, however, a proportional compensation is allowed in terms of the journeys made and the time spent during the process.

Sometimes, treatment may be cancelled due to an excess or a lack of ovarian response to the hormonal treatment. However, it could also be caused by other circumstances.


How can I get further information?

Opening hours: Monday – Friday from 8am to 9pm, weekends and public holidays from 10 am to 1pm.

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Telephone number: +34 93 227 98 98